Cat.#:KB-E13251M
Regulatory Status:RUO
Alternative:HARP; ARP2; Angiopoietin-Related Protein 2
Alternative:
Detection Method:
ELISA
Assay Type:
Sandwich
Detection Range:
0.31-20ng/mL
Sensitivity:
0.12ng/mL
Specificity:
This kit recognizes Mouse ANGPTL2 in samples. No significant cross-reactivity or interference between Mouse ANGPTL2 and analogues was observed.
Sample Type:
Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids
Research Area:
Cancer
Angiopoietin-related protein 2 also known as angiopoietin-like protein 2 is a protein that is encoded by the ANGPTL2 gene.Angiopoietin-like protein 2 maintains tissue homeostasis by promoting adaptive inflammation and subsequent tissue reconstruction, whereas an excess of ANGPTL2 activation induced by prolonged stress promotes the breakdown of tissue homeostasis due to chronic inflammation, promoting the development of metabolic diseases. ANGPTL2 has a role also in angiogenesis, in tissue repair, in obesity, in atherosclerotic diseases and finally in carcinogenesis.
As the OD values of the standard curve may vary according to the conditions of the actual assay performance (e.g. operator, pipetting technique, wash technique or temperature effects), the operator should establish a standard curve for each test. Typical standard curve and data are provided below for reference only.
Intra-assay Precision (Precision within an assay):CV% < 10%; Inter-assay Precision (Precision between assays):CV% < 10%
The recovery of Mouse ANGPTL2 spiked at three different levels in samples throughout the range of the assay was evaluated in various matrices.
Samples were spiked with high concentrations of Mouse ANGPTL2 and diluted with Universal Diluent to produce samples with values within the range of the assay.
CATALOGUE