Name: ER STRESS Small Molecule Compound Kit-1
Specification: 10*1mL(10mM) ; 10*2mg ; 10*5mg
Storage conditions: Store at -20℃
Shipping conditions: Freeze transportation
Product Introduction
| CAS number | Product number | Product name | Molecular formula | molecular weight | Corresponding target | Product Description |
| 27208-80-6 | IP0770 | Polydatin; polydatin | C20H22O8 | 390.38 | IS Stress | Found in the traditional Chinese medicine Polygonum cuspidatum root, it has anti-inflammatory effects in multiple experimental models. Reported to inhibit G6PD and induce oxidative and endoplasmic reticulum stress |
| 14605-22-2 | IT0790 | Tauroursodeoxycholic acid; tauroursodeoxycholic acid | C26H45NO6S | 499.7 | IS Stress | Is an endoplasmic reticulum stress inhibitor. |
| 35807-85-3 | IT0370 | Tauroursodeoxycholate Sodium; Sodium tauroursodeoxycholate | C26H44NNaO6S | 521.69 | ER Stress,Caspase | It is an endoplasmic reticulum stress inhibitor that can significantly reduce the expression of apoptotic molecules such as caspase-3 and caspase-12. |
| 1716-12-7 | IS0080 | Sodium 4-phenylbutyrate; 4-phenylbutyrate sodium salt | C10H11NaO2 | 186.18 | IS Stress | It is a histone deacetylase (HDAC) and endoplasmic reticulum stress (ER) inhibitor that can be used in the research of diseases such as cancer and infection. |
| 73-31-4 | IM0080 | Melatonin; melatonin | C 13 H 16 N 2 O 2 | 232.28 | ATF6 | Is a hormone that activates melatonin receptors. It is also a new type of selective ATF-6 inhibitor. |
| 1589527-65-0 | IK0470 | KIRA6 | C 28 H 25 F 3 N 6 O | 518.53 | IRE1 | It is a potent inhibitor of type II IRE1α kinase. |
| 14003-96-4 | IM2400 | 8-Formyl-7-Hydroxy-4-Methyl-Coumarin; 8-Formyl-7-hydroxy-4-methylcoumarin | C11H8O4 | 204.18 | IRE1 | It is a highly efficient and selective IRE1 RNase inhibitor. |
| 307543-71-1 | IS1990 | STF083010 | C15H11NO3S2 | 317.38 | IRE1 | It is a specific IRE1α endonuclease inhibitor. |
| 1337532-29-2 | IG1320 | GSK2656157 | C23H21FN6O | 416.45 | PERK | It is a selective, ATP-competitive PERK inhibitor. |
| 1337531-36-8 | IG1330 | GSK2606414 | C24H20F3N5O | 451.44 | PERK | It is a PERK inhibitor . |
This set selects several compounds commonly used in endoplasmic reticulum stress-related research to facilitate customers' preliminary screening and other operations. Customers can also flexibly customize exclusive Kits according to their own needs.
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Things to note
Considerations
1. This product is for scientific research use only. Do not use it for medicine, clinical diagnosis or treatment, food and cosmetics, etc. Do not store in ordinary residential areas.
2. For your safety and health, please wear a lab coat, disposable gloves and a mask.
3. The experimental results can be affected by many factors. The relevant processing is limited to the product itself and does not involve other compensation.